Manufactured by:BT LAB
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CP46A Polyclonal Antibody

CP46A Polyclonal Antibody

SKU:
ABM196328
Manufacturer SKU
BT-AP15085
Product type
Primary Antibodies
TargetCYP46A1
ApplicationsWB, ELISA
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

Key facts & specifications
Research areas
Cancer, Metabolism, Signal Transduction, Neuroscience
Also known as
Cholesterol 24-hydroxylase ;CH24H;EC 1.14.13.98;Cytochrome P450 46A1
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; ELISA: 1: 5000 - 1: 20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 180-260
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
100ul, 50ul, 20ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-AP15085
Gene ID
10858
UniProt accession
Q9Y6A2
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

BT LAB
£207.05£176.00