Manufactured by:BT LAB
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TNR8 Polyclonal Antibody

TNR8 Polyclonal Antibody

SKU:
ABM196253
Manufacturer SKU
BT-AP15059
Product type
Primary Antibodies
TargetTNFRSF8
ApplicationsWB, ELISA, IHC-P, IF/ICC
Species / reactivityHuman, Rat, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Key facts & specifications
Research areas
Signal Transduction
Also known as
Tumor necrosis factor receptor superfamily member 8 ;CD30L receptor;Ki-1 antigen;Lymphocyte activation antigen CD30;CD antigen CD30
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; ELISA: 1: 20000
Immunogen
Synthesized peptide derived from part region of human protein
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
100ul, 50ul, 20ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBELISAIHC-pIF
Applications
Identifiers & database references
Manufacturer SKU
BT-AP15059
Gene ID
943
UniProt accession
P28908
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

TNFRSF8TNF receptor superfamily member 8

View target guide

TNFRSF8 identifies TNF receptor superfamily member 8 in Homo sapiens (Human). This target record connects NCBI Gene 943, UniProtKB P28908 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
943
UniProtKB
P28908
BT LAB
£207.05£176.00