Manufactured by:BT LAB
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PF-4 Polyclonal Antibody

PF-4 Polyclonal Antibody

SKU:
ABM190208
Manufacturer SKU
BT-AP12959
Product type
Primary Antibodies
TargetPF4
ApplicationsIHC-P, ELISA, IF/ICC
Species / reactivityHuman, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum.

Key facts & specifications
Research areas
Cardiovascular, Immunology, Cancer
Also known as
Platelet factor 4 ;PF-4;C-X-C motif chemokine 4;Iroplact;Oncostatin-A [Cleaved into: Platelet factor 4, short form]; Platelet factor 4; PF-4; C-X-C motif chemokine 4; Iroplact; Oncostatin-A; Platelet factor 4, short form;
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
IHC-p: 1: 50 - 1: 200; ELISA: 1: 10000 - 1: 20000
Immunogen
Synthetic peptide from human protein at AA range: 51-100
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceIHC-pELISAIF
Applications
Identifiers & database references
Manufacturer SKU
BT-AP12959
Gene ID
5196
UniProt accession
P02776
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

PF4platelet factor 4

View target guide

PF4 identifies platelet factor 4 in Homo sapiens (Human). This target record connects NCBI Gene 5196, UniProtKB P02776 and related ABMIUM catalogue products.

Biological function: PF4 (CXCL4) is a platelet-released chemokine involved in chemotactic and inflammatory responses and in regulation of haematopoietic and vascular cell behaviour. It also binds heparin and can modulate anticoagulant activity.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
5196
UniProtKB
P02776
BT LAB
£81.31£69.00