Manufactured by:BT LAB
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6CKine Polyclonal Antibody

6CKine Polyclonal Antibody

SKU:
ABM176947
Manufacturer SKU
BT-AP08504
Product type
Primary Antibodies
TargetCCL21
ApplicationsIHC-P, ELISA, IF/ICC
Species / reactivityHuman, Rat, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells| but not for B cells| macrophages| or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

Key facts & specifications
Research areas
Immunology
Also known as
C-C motif chemokine 21 (6Ckine;Beta-chemokine exodus-2;Secondary lymphoid-tissue chemokine;SLC;Small-inducible cytokine A21); C-C motif chemokine 21; 6Ckine; Beta-chemokine exodus-2; Secondary lymphoid-tissue chemokine; SLC; Small-inducible cytokine A21)
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
IHC-p: 1: 50 - 1: 200; ELISA: 1: 10000 - 1: 20000
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CCL21. AA range:71-120
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceIHC-pELISAIF
Applications
Identifiers & database references
Manufacturer SKU
BT-AP08504
Gene ID
6366
UniProt accession
O00585
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

CCL21C-C motif chemokine ligand 21

View target guide

CCL21 identifies C-C motif chemokine ligand 21 in Homo sapiens (Human). This target record connects NCBI Gene 6366, UniProtKB O00585 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
6366
UniProtKB
O00585
BT LAB
£81.31£69.00