Manufactured by:BT LAB
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PI 3-kinase p85 Alpha Polyclonal Antibody

PI 3-kinase p85 Alpha Polyclonal Antibody

SKU:
ABM172906
Manufacturer SKU
BT-AP07140
Product type
Primary Antibodies
TargetPIK3R1
ApplicationsIHC, IF/ICC, ELISA, WB, IHC-P
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Background

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1 results in four transcript variants encoding different isoforms.

Key facts & specifications
Research areas
Signal Transduction
Also known as
PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
IHC: 1: 100 - 1: 300; IF: 1: 200 - 1: 1000; ELISA: 1: 5000
Immunogen
The antiserum was produced against synthesized peptide derived from human PI3-kinase p85-alpha. AA range:573-622
Molecular weight
83598
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceIHCIFELISAWBIHC-p
Applications
Identifiers & database references
Manufacturer SKU
BT-AP07140
Gene ID
5295
UniProt accession
P27986
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

PIK3R1phosphoinositide-3-kinase regulatory subunit 1

View target guide

PIK3R1 identifies phosphoinositide-3-kinase regulatory subunit 1 in Homo sapiens (Human). This target record connects NCBI Gene 5295, UniProtKB P27986 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
5295
UniProtKB
P27986
BT LAB
£81.31£69.00