Manufactured by:BT LAB
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JAK1(phospho Tyr1022) Polyclonal Antibody

JAK1(phospho Tyr1022) Polyclonal Antibody

SKU:
ABM171874
Manufacturer SKU
BT-AP06784
Product type
Primary Antibodies
TargetJAK1
ApplicationsWB, IHC-P, IF/ICC, ELISA
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.

Key facts & specifications
Research areas
Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction
Also known as
Tyrosine-protein kinase JAK1; JAK1; JAK1A; JAK1B; Tyrosine-protein kinase JAK1; Janus kinase 1; JAK-1
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC-p: 1: 100 - 1: 300; IF: 1: 50 - 1: 200; ELISA: 1: 10000
Immunogen
The antiserum was produced against synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022. AA range:988-1037
Molecular weight
131957
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
100ul, 50ul, 20ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pIFELISAICC
Applications
Identifiers & database references
Manufacturer SKU
BT-AP06784
Gene ID
3716
UniProt accession
P23458
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

JAK1Janus kinase 1

View target guide

JAK1 identifies Janus kinase 1 in Homo sapiens (Human). This target record connects NCBI Gene 3716, UniProtKB P23458 and related ABMIUM catalogue products.

Organism
Homo sapiens (Human)
NCBI Gene
3716
UniProtKB
P23458
BT LAB
£207.05£176.00