Manufactured by:BT LAB
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MMP-8 Polyclonal Antibody

MMP-8 Polyclonal Antibody

SKU:
ABM168130
Manufacturer SKU
BT-AP05488
Product type
Primary Antibodies
TargetMMP8
ApplicationsWB, IHC, ELISA, IHC-P
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

MMP8 encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. Alternative splicing results in multiple transcript variants.

Key facts & specifications
Research areas
Cardiovascular
Also known as
MMP8; CLG1; Neutrophil collagenase; Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CL
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC: 1: 100 - 1: 300; ELISA: 1: 20000
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP-8. AA range:418-467
Molecular weight
53412
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHCELISAIHC-p
Applications
Identifiers & database references
Manufacturer SKU
BT-AP05488
Gene ID
4317
UniProt accession
P22894
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

MMP8matrix metallopeptidase 8

View target guide

MMP8 identifies matrix metallopeptidase 8 in Homo sapiens (Human). This target record connects NCBI Gene 4317, UniProtKB P22894 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
4317
UniProtKB
P22894
BT LAB
£81.31£69.00