Manufactured by:BT LAB
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TTF-1(Phospho-Ser327) Rabbit Polyclonal Antibody

TTF-1(Phospho-Ser327) Rabbit Polyclonal Antibody

SKU:
ABM167596
Manufacturer SKU
BT-AP05309
Product type
Primary Antibodies
TargetNKX2-1
ApplicationsWB
Species / reactivityHuman, Rat, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea| choreoathetosis| congenital hypothyroidism| and neonatal respiratory distress| and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene| transcription termination factor 1| which plays a role in ribosomal gene transcription.

Key facts & specifications
Research areas
Epigenetics and Nuclear Signaling
Also known as
TTF-1 ;Ser327; Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 1000 - 1: 2000
Immunogen
Synthesized phosho peptide around human TTF-1 (Ser327)
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWB
Applications
Identifiers & database references
Manufacturer SKU
BT-AP05309
Gene ID
7080
UniProt accession
P43699
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

NKX2-1NK2 homeobox 1

View target guide

NKX2-1 identifies NK2 homeobox 1 in Homo sapiens (Human). This target record connects NCBI Gene 7080, UniProtKB P43699 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
7080
UniProtKB
P43699
BT LAB
£81.00£69.00