Manufactured by:BT LAB
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IL-3R Alpha Polyclonal Antibody

IL-3R Alpha Polyclonal Antibody

SKU:
ABM165169
Manufacturer SKU
BT-AP04498
Product type
Primary Antibodies
TargetIL3RA
ApplicationsWB, ELISA, IHC-P
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

Interleukin-3 receptor subunit alpha encoded by IL3RA is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.

Key facts & specifications
Research areas
Immunology
Also known as
IL3RA; IL3R; Interleukin-3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; CD123
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; ELISA: 1: 10000; IHC-p: 100 - 300
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human IL3RA. AA range:241-290
Molecular weight
41580
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBELISAIHC-p
Applications
Identifiers & database references
Manufacturer SKU
BT-AP04498
Gene ID
3563
UniProt accession
P26951
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

IL3RAinterleukin 3 receptor subunit alpha

View target guide

IL3RA identifies interleukin 3 receptor subunit alpha in Homo sapiens (Human). This target record connects NCBI Gene 3563, UniProtKB P26951 and related ABMIUM catalogue products.

Organism
Homo sapiens (Human)
NCBI Gene
3563
UniProtKB
P26951
BT LAB
£81.00£69.00