Manufactured by:BT LAB
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GSK3Beta Polyclonal Antibody

GSK3Beta Polyclonal Antibody

SKU:
ABM163225
Manufacturer SKU
BT-AP03850
Product type
Primary Antibodies
TargetGSK3B
ApplicationsWB, IHC, IHC-P
Species / reactivityMouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

Glycogen synthase kinase 3 beta encoded by GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of GSK3B may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for GSK3B.

Key facts & specifications
Research areas
Neuroscience
Also known as
GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 1000 - 2000; IHC: 1: 200 - 500
Immunogen
Recombinant Protein of GSK3β
Molecular weight
46744
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHCIHC-p
Applications
Identifiers & database references
Manufacturer SKU
BT-AP03850
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

GSK3Bglycogen synthase kinase 3 beta

View target guide

GSK3B identifies glycogen synthase kinase 3 beta in Homo sapiens (Human). This target record connects NCBI Gene 2932, UniProtKB P49841 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
2932
UniProtKB
P49841
BT LAB
£81.31£69.00