Manufactured by:Elabscience
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Rekombinantes humanes HMGB1 Protein

Rekombinantes humanes HMGB1-Protein, geliefert von Elabscience mit technischen Spezifikationen des Kooperationspartners.

SKU:
ABM17265-1
Manufacturer SKU
PKSH032544_10ug
Product type
Zytokine
TargetHMGB1
Species / reactivityMensch
Purity> 95 % bestimmt mittels reduzierender SDS-PAGE.

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Recombinant Human HMGB1 Protein is a research-use recombinant protein from Elabscience preparation representing HMGB1 supplied as Lyophilized. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.

Key facts & specifications
Research areas
Epigenetics and Nuclear Signaling
Also known as
HMG-1, HMG1, HMGB1, High Mobility Group Protein 1, High Mobility Group Protein B1
Modification
N-MARI
Molecular weight
10,0 kDa
Form / buffer
Lyophilisiert aus einer 0,2 μm filtrierten Lösung von 50mM HEPES-Na, 500mM NaCl, 0,6mM DTT, pH 7,9.
Normalerweise werden vor der Lyophilisierung 5% - 8% Trehalose, Mannitol und 0,01% Tween 80 als Schutzstoffe zugesetzt.
Bitte beachten Sie die spezifischen Pufferinformationen im gedruckten Handbuch.
Endotoxin level
< 1,0 EU pro μg des Proteins, bestimmt nach der LAL-Methode.
Sequence
Pro92-Val176
Technical note
Bitte beachten Sie das gedruckte Handbuch für detaillierte Informationen.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesBioaktivitätBindungZellbasiertIn VivoELISA-Capture
Human
Identifiers & database references
Manufacturer SKU
PKSH032544_10ug
Gene symbol
HMGB1
Gene ID
3146
UniProt accession
P09429
Storage, stability & shipping
Shelf life
12 Monate
Shipped at
Dieses Produkt wird als lyophilisiertes Pulver geliefert, das mit Kühlakkus versandt wird.
Short-term storage
Im Allgemeinen sind lyophilisierte Proteine bis zu 12 Monate stabil, wenn sie bei -20 bis -80 ℃ gelagert werden. Rekonstituierte Proteinlösung kann 2-7 Tage bei 4-8 ℃ gelagert werden. Aliquots von rekonstituierten Proben sind bei < -20 ℃ 3 Monate lang stabil.
Long-term storage
Im Allgemeinen sind lyophilisierte Proteine bis zu 12 Monate stabil, wenn sie bei -20 bis -80 ℃ gelagert werden. Rekonstituierte Proteinlösung kann 2-7 Tage bei 4-8 ℃ gelagert werden. Aliquots von rekonstituierten Proben sind bei < -20 ℃ 3 Monate lang stabil.
Aliquoting guidance
Den gesamten Flascheninhalt sofort rekonstituieren. Arbeitslösung aliquotieren; wiederholtes Einfrieren und Auftauen vermeiden.
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

HMGB1high mobility group box 1

View target guide

HMGB1 identifies high mobility group box 1 in Homo sapiens (Human). This target record connects NCBI Gene 3146, UniProtKB P09429 and related ABMIUM catalogue products.

Biological function: HMGB1 is a multifunctional, redox-sensitive chromatin-associated protein. In the nucleus it acts as a DNA chaperone in transcription, replication, chromatin remodelling and DNA repair; extracellular or cytoplasmic HMGB1 can also participate in inflammatory and innate immune signalling.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
3146
UniProtKB
P09429
Elabscience
£66.00£52.80