Human ApoB (Apolipoprotein B) CLIA Kit mit durch Kollaborateure getesteten Probenmatrix-Nachweisen von Elabscience.
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Human ApoB (Apolipoprotein B) CLIA Kit from Elabscience is intended for research workflows involving ApoB. Review the listed specifications and supporting documents to confirm compatibility with the intended method.
This product is manufactured by Elabscience and sold through ABMIUM without relabelling.
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APOB (apolipoprotein B) encodes the major structural apolipoprotein of chylomicrons and low-density lipoproteins. Human APOB gives rise to two principal plasma forms: ApoB-100, synthesized mainly in the liver and acting as a ligand for the LDL receptor, and ApoB-48, produced in the intestine through RNA editing. Researchers use APOB to investigate lipoprotein particle biology, lipid transport and receptor-mediated clearance.
Biological function: Apolipoprotein B provides the core protein scaffold for major circulating lipoprotein particles. ApoB-100 is the full-length hepatic form found in LDL and functions as a recognition ligand for LDL-receptor-mediated particle uptake. ApoB-48 is the shorter intestinal form in chylomicrons and is generated from the same APOB transcript by RNA editing that introduces an early stop codon. These forms link APOB to transport of triglyceride- and cholesterol-rich particles between tissues.
