ABMIUM target intelligence

F3

coagulation factor III, tissue factor

Coagulation factor III (F3), better known as tissue factor or CD142, is a membrane glycoprotein that initiates the extrinsic coagulation pathway. ABMIUM catalogue products linked below support research on tissue factor/F3 biology.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene2152 UniProtP13726

ABMIUM research catalogue

Research Products

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Research context & evidence

About F3

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

Coagulation factor III (F3/tissue factor/CD142) is the cellular receptor and cofactor for coagulation factor VII/VIIa. Formation of the tissue factor-factor VIIa complex initiates the extrinsic coagulation cascade and promotes activation of factors IX and X, linking tissue injury to thrombin generation and haemostasis.

Experimental context

Research context

Tissue factor (F3/coagulation factor III/CD142) is commonly studied in coagulation, thrombosis, vascular biology, haemostasis and inflammation-associated tissue-factor signalling. Use the catalogue filters below to review ABMIUM products associated with F3, then confirm species, sample type, assay format, application and product-level validation before use.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

TFTissue factorCD142TFACf-3