ABMIUM target intelligence

C3

complement C3

C3 (complement C3) is the central complement precursor cleaved into C3a and C3b, linking complement activation to inflammatory signalling, opsonization and downstream C5 activation.

Read full target overview
OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene718 UniProtP01024

C3 products

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Anti-C3 Antibody Picoband® Boster Bio
Boster BioABMIUM Verified™

Anti-C3-Antikörper Picoband®

SKU: ABM23407-1Primärantikörper
Target
Komplement C3
Reactivity
Mensch,Maus,Ratte
Applications
ELISA,Durchflusszytometrie,IHC,IHC-P,WB
Host
Kaninchen
From£278.80£328.00 Save 15%
Available to order
Comparing

Research context & evidence

About C3

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

Complement C3 is activated by C3 convertases across the classical, lectin and alternative pathways. Cleavage generates C3a, an anaphylatoxin involved in inflammatory signalling, and C3b, which covalently labels surfaces for opsonization, supports complement amplification and contributes to C5 convertase formation. Additional processing generates iC3b and other fragments with distinct immune functions.

Experimental context

Research context

C3 is a core target in studies of innate immunity, complement activation and amplification, opsonization, inflammatory signalling and terminal-pathway engagement. Assays should distinguish intact C3 from activation fragments such as C3a, C3b and iC3b because abundance and interpretation depend on specimen handling and assay specificity.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Complement C3C3aComplement Component C3aAHUS5ARMD9ASPC3bCO3CPAMD1HEL-S-62pHSE-MSFPlp