ABM-16164
CollaboratorElabscience
Target
IL-21RPurity
>92% by SDS-PAGEMol. weight
26.5 kDaActivity
1. Measured by its ability to bind human IL-21 in a funct...Species
Human
1. Measured by its ability to bind human IL-21 in a functional ELISA. 2. Measured by its ability to inhibit IL21-induced Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is typically 1-5 ng/ml in the presence of 10 ng/ml of recombinant human IL23. Measured by its ability to inhibit IL21-induced Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is typically 50-200 pg/mL in the presence of 1 ng/ml of recombinant human IL21.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.