Recombinant Human IL-36 Beta/IL-1F8(157AA)
Recombinant Human IL-36 Beta/IL-1F8(157AA) supplied by Elabscience with collaborator-provided technical specifications. Read more ›
["Measured by its ability to induce IL-8 secretion in A431 human epithelial carcinoma cells. The ED50 for this effect is 275.14 ng/ml. ,18 kDa"]Product Description
IL-36 Beta is the stated recombinant protein target for this Elabscience product. The listing uses collaborator-supplied specifications to support research-use-only protein selection through ABMIUM.
Protein profile: reactive species/source: Human; expression system: E.coli; physical form: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.; tag: Human ,IL-36 Beta ,Cytokines; predicted molecular weight: 17.7 kDa.
Quality and formulation: purity: > 95 % as determined by reducing SDS-PAGE.; endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method..
Functional evidence: activity: Measured by its ability to induce IL-8 secretion in A431 human epithelial carcinoma cells. The ED<sub>50</sub> for this effect is 275.14 ng/ml.. In the ABMIUM matrix, collaborator-supplied functional evidence is marked C; unsupported application columns remain N.
Sequence coverage: 17.7 kDa.
Database references: UniProt: Q9NZH7-2 | NCBI Gene: 27177 | Gene symbol: IL-36 Beta.
Research Use Only.
Key Facts
| Target | IL-36 Beta |
| Also known as | IL1H, IL1F, Interleukin-1 family member, IL-1F, IL-1H, Fil1e, IL-1 eta, IL-1F8, IL-1H2, IL-36 Beta, Interleukin-1 family member 8, Interleukin-36 beta, IL1F8, IL1H2, IL36B, 2310043N20Rik, Family of interleukin 1 eta, FIL1, FIL1 (ETA), FIL1 eta, FIL1H, FILI-(ETA), IL 1F8, IL 1F8 (FIL1 eta, IL 1H2, IL1 ETA, IL1F8 (Canonical product IL 1F8a), Interleukin 1 family, Interleukin 1 homolog 2, Interleukin 1 Superfamily e, Interleukin 36 beta, Interleukin-1 eta, Interleukin-1 homolog 2, member 8, member 8 (eta), MGC126880, MGC126882, OTTMUSP00000012797, RP23-176J12.1 |
| Species reactivity | Human |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Form / buffer | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Shelf life | 12 months |
| Research area | Immunology |
| BIOACTIVITY | BINDING | CELL-BASED | IN VIVO | ELISA CAPTURE | |
|---|---|---|---|---|---|
| Human |
Specifications
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Storage & Stability
Compliance & Certifications
Manufactured under ISO 9001:2015 quality management standards.
Manufactured under ISO 14001:2015 quality management standards.
Manufactured under ISO 45001:2018 quality management standards.
Not intended for diagnostic or therapeutic use.
Substance does not appear on the SVHC candidate list.