Rat E-Cadherin/CDH1/Cadherin-1 ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›
Product Description
Cadherin-1, also known as CAM 120/80 or epithelial cadherin (E-cadherin) or uvomorulin, is a protein that in humans is encoded by the CDH1 gene. E-cadherin is a Ca (2+)-dependent epithelial cell-cell adhesion molecule. Downregulation of E-cadherin expression often correlates with strong invasive potential and poor prognosis of human carcinomas. The gene spans a region of approximately 100 kb, and its location on chromosome 16q22.1. It contains 16 exons and a 65-kb-long intron 2. E-cadherin gene mutations may contribute to the development of diffusely growing gastric carcinomas. It plays a central part in the process of epithelial morphogenesis and acts as a strong invasion suppressor in experimental tumor cell systems. The standard product used in this kit is recombinant gene expression with the molecular mass of 120KDa.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK1434 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Rat |
| Tested applications | ELISA |
| Gene name | Cdh1 |
| Protein name | Cadherin-1 |
| Sample type | cell culture supernatants, serum and plasma (heparin). |
| Assay range | 156 pg/ml - 10,000 pg/ml |
| Sensitivity | <15 pg/ml |
| Specificity | Natural and recombinant rat E-Cadherin |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: Q24-S704 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | Q9R0T4 |
| NCBI Gene ID | 83502 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Cadherin-1 |
| Also known as | Arc 1; Cadherin 1; CD324; CDH1; CDHE; E cadherin; ECAD; E-cad; E-cadherin; LCAM; UVO; Uvomorulin |
| Species reactivity | Rat |
| Purity | Natural and recombinant rat E-Cadherin |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <15 pg/ml |
| Detection range | 156 pg/ml - 10,000 pg/ml |
| Sample types |
cell culture supernatantsserum and plasma (heparin).
See sample validation ›
|
Sample Type Validation
2 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (heparin). |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.