Rabbit Endothelin 1/EDN1 ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›
Product Description
The endothelins is a family of structurally and pharmacologically distinct peptides, which has been identified and sequenced in humans. Three isoforms of rabbit endothelin have been identified: endothelin-1, -2, and -3. Endothelin-1 is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis. Endothelins are implicated in vascular diseases of several organ systems, including the heart, general circulation and brain. Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure (hypertension) and heart disease.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK0952-RB |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Rabbit |
| Tested applications | ELISA |
| Gene name | EDN1 |
| Protein name | Endothelin-1 |
| Sample type | cell culture supernatants, serum and plasma (heparin, EDTA). |
| Assay range | 3.9 pg/ml - 250 pg/ml |
| Sensitivity | <0.5 pg/ml |
| Immunogen | A peptide reflecting the target protein in rabbit. Sequence: C53-W73 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | P29560 |
| NCBI Gene ID | 100009270 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Endothelin-1 |
| Also known as | Endothelin-1;ET-1;Preproendothelin-1;PPET1;Edn1; |
| Species reactivity | Rabbit |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <0.5 pg/ml |
| Detection range | 3.9 pg/ml - 250 pg/ml |
| Sample types |
cell culture supernatantsserum and plasma (heparinEDTA).
See sample validation ›
|
Sample Type Validation
3 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (heparin | |||||
| EDTA). |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.