Mouse TPOR/MPL/Thrombopoietin R ELISA Kit PicoKine®

Mouse TPOR/MPL ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Mpl in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 15pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

The thrombopoietin receptor (TPOR), also known as CD110, is a protein that in humans is encoded by the MPL (myeloproliferative leukemia virus) oncogene. The human MPL gene is mapped to chromosome 1p34. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1436
Product category	PicoKine® ELISA Kits
Reactive species	Mouse
Tested applications	ELISA
Gene name	Mpl
Protein name	Thrombopoietin receptor
Sample type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Assay range	156 pg/ml - 10,000 pg/ml
Sensitivity	<15 pg/ml
Specificity	Natural and recombinant mouse TPOR
Immunogen	Expression system for standard: NS0; Immunogen sequence: Q26-W482
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	Q08351
NCBI Gene ID	17480

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.