ELISA Kit supplied by Boster Bio Read more ›
Mouse Meteorin-like/METRNL ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Meteorin-like protein in Cell culture supernatant, Cell lysates, serum and plasma (heparin, EDTA). samples from Mouse. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.
Mouse Meteorin-like/METRNL ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Metrnl in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 12pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.METRNL (Meteorin-like) is a cytoplasmic 30 kDa (predicted) member of the meteorin family of proteins. It is expressed by neurons, and appears to function as a primer molecule that sets the stage for either cell differentiation or neurite outgrowth when it acts with Dclk1 and SerpinB1. In mice, exogenously elevated circulating Metrnl increased whole-body energy expenditure and improved glucose tolerance following diet-induced obesity. It also induced expression of antiinflammatory genes, leading to alternative activation of macrophages in adipose tissue and to browning of white fat depots. Metrnl did not appear to activate thermogenic genes ly, but it stimulated eosinophils and macrophages to enter adipose tissue and take their specific thermogenic actions. Blockade of cytokine signaling eliminated Metrnl-induced changes in gene expression required for alternative macrophage activation and blunted expression of beige fat thermogenic and beta-oxidation genes. It is concluded that METRNL is a hormone that influences energy expenditure and thermogenic programs in adipose tissue.
| Collaborator | Boster Bio |
| Partner model | EK1550 |
| Target | Meteorin-like protein |
| Reactivity | Mouse |
| Applications | ELISA |
| Cross-reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: Q46-E311 |
| Sample types | Cell culture supernatant,Cell lysates,serum and plasma (heparin,EDTA). |
| Detection range | 62.5 pg/ml - 4,000 pg/ml |
| Sensitivity | <12 pg/ml |
| Purity | Natural and recombinant mouse Meteorin-like |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Availability | Available |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
For research applications. Not for diagnostic use.
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