Mouse LDLR / OLR1 ELISA Kit PicoKine®

Mouse LDLR / OLR1 ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Low-density lipoprotein receptor in Cell culture supernatant, Serum, plasma (heparin) and urine. samples from Mouse. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.

Mouse LDLR / OLR1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ldlr in cell culture supernatants, serum, plasma (heparin) and urine. Sensitivity: 12pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

The Low-Density Lipoprotein (LDL) Receptor is a mosaic protein of 839 amino acids (after removal of 21-amino acid signal peptide) that mediates the endocytosis of cholesterol-rich LDL. In humans, the LDL receptor protein is encoded by the LDLR gene. It belongs to the Low density lipoprotein receptor gene family. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.

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