ELISA Kit supplied by Boster Bio Read more ›
Mouse IGF-1 ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Insulin-like growth factor 1 in Cell culture supernatant, Cell lysates, serum and plasma (heparin, EDTA). samples from Mouse. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.
Mouse IGF-1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Igf1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 5pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.Insulin-like growth factor 1 (IGF-1) that was once called somatomedin C, is a polypeptide protein hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. Human IGF1 is a single chain 70-amino acid polypeptide cross-linked by 3 disulfide bridges, with a calculated molecular mass of 7.6 kD.1 The IGF1 gene, mapped on 12q22-q24. contains 5 exons. Exons 1-4 encode the 195-amino acid precursor (IGF1B), and exons 1, 2, 3, and 5 encode the 153-residue peptide (IGF1A). The structure of IGF1 resembles that of IGF2. And the IGF1 and IGF2 genes have complex structures with multiple promoters. The expression of both genes is regulated at the levels of transcription, RNA processing, and translation. IGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. Moreover, approximately 98% of IGF-1 is always bound to one of 6 binding proteins (IGF-BP). Furthermore, IGF-1 is one of the most potent natural activators of the AKT signaling pathway, a stimulator of cell growth and multiplication and a potent inhibitor of programmed cell death.
| Collaborator | Boster Bio |
| Partner model | EK0378 |
| Target | Insulin-like growth factor 1 |
| Reactivity | Mouse |
| Applications | ELISA |
| Cross-reactivity | There is no detectable cross-reactivity with IGF-2. |
| Immunogen | Expression system for standard: E.coli; Immunogen sequence: G49-A118 |
| Sample types | Cell culture supernatant,Cell lysates,serum and plasma (heparin,EDTA). |
| Detection range | 62.5 pg/ml - 4,000 pg/ml |
| Sensitivity | <5 pg/ml |
| Purity | Natural and recombinant mouse IGF-1 |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Availability | Available |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
For research applications. Not for diagnostic use.
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