ELISA Kit supplied by Boster Bio Read more ›
Mouse DcTRAILR2/TNFRSF22 ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Tumor necrosis factor receptor superfamily member 22 in Cell culture supernatant, serum and plasma (heparin, EDTA, citrate). samples from Mouse. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.
Mouse DcTRAILR2/TNFRSF22 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Tnfrsf22 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.TNFRSF22 interacts via a complex receptor system to preferentially induce apoptosis of tumor cells in vivo and in vitro. This gene is mapped to 7 F5; 7 88.27 cM. The mouse decoy TRAIL R2 (TNFRSF22) gene encodes a 198 amino acid (aa) residues type I transmembrane protein with a putative 39 aa signal peptide, a 136 aa extracellular domain, a 18 aa transmembrane region, and a 5 aa cytoplasmic tail. An alternatively spliced variant encoding a secreted soluble receptor of 180 aa has also been described. The transmembrane and soluble receptors are known as mDcTRAIL R2L and mDcTRAIL R2S, respectively. Both mDcTRAIL R2 isoforms and the GPI-linked mDcTRAIL R1 bind TRAIL specifically but are incapable of triggering signal transduction. Mouse DcTRAIL R1 and mDcTRAIL R2 share 71% sequence identity. The two receptors have similar structural modules in their CRDs, which differ from those found in the CRDs of mTNF RH3. Mouse DcTRAIL R1 preferentially binds mTRAIL while mDcTRAIL R2 binds both human and mTRAIL. mRNA of mouse DcTRAIL R1 and -2 are expressed at low levels in many mouse tissues and at higher levels in several mouse cell lines.
| Collaborator | Boster Bio |
| Partner model | EK2007 |
| Target | Tumor necrosis factor receptor superfamily member 22 |
| Reactivity | Mouse |
| Applications | ELISA |
| Cross-reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: E42-R198 |
| Sample types | Cell culture supernatant,serum and plasma (heparin,EDTA,citrate). |
| Detection range | 15.6 pg/ml - 1,000 pg/ml |
| Sensitivity | <10 pg/ml |
| Purity | Natural and recombinant mouse TNFRSF22 |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Availability | Available |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
For research applications. Not for diagnostic use.
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