Mouse CXCL10/IP-10 PicoKine® Quick ELISA Kit
ELISA Kit supplied by Boster Bio Read more ›
Product Description
Chemokine(C-X-C motif) ligand 10(CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein(gamma-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis.It is a potent inhibitor of angiogenesis in vivo. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. It is a RAS target gene and is overexpressed in the majority of colorectal cancers.This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | FEK0736 |
| Product category | Quick ELISA Kits |
| Reactive species | Mouse |
| Tested applications | ELISA, IP |
| Gene name | CXCL10 |
| Protein name | C-X-C motif chemokine 10 |
| Sample type | cell culture supernatants, serum and plasma(heparin). |
| Assay range | 31.2 pg/ml - 2,000 pg/ml |
| Sensitivity | <1 pg/ml |
| Immunogen | Expression system for standard: E.coli; Immunogen sequence: I22-P98 |
| Storage | Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.) |
| UniProt | P17515 |
| NCBI Gene ID | 15945 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | C-X-C motif chemokine 10 |
| Also known as | C X C motif chemokine 10; C7; crg 2; CXCL10; CXCL10/IP10; Gamma IP10; gIP 10; IFI10; INP10; IP 10; IP10; mob 1; SCYB10; Small inducible cytokine B10 |
| Species reactivity | Mouse |
| Shelf life | Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.) |
| Sensitivity | <1 pg/ml |
| Detection range | 31.2 pg/ml - 2,000 pg/ml |
| Sample types |
cell culture supernatantsserum and plasma(heparin).
See sample validation ›
|
Sample Type Validation
2 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma(heparin). |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.