Mouse BMP-2 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Mouse BMP-2 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Mouse BMP2 in bone tissue, cell culture supernatants and serum.

Bone morphogenetic protein-2 (BMP-2, BMP 2A) belongs to the transforming growth factor beta (TGF-beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice. BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase (MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis. Bone morphogenic proteins (BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion. The standard product used in this kit is recombinant mouse BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EZ0313
Product category	EZ-Set™ ELISA Kits (Ab Pairs)
Reactive species	Mouse
Tested applications	ELISA
Gene name	BMP2
Protein name	Bone morphogenetic protein 2
Sample type	bone tissue, cell culture supernatants and serum.
Assay range	31.2 pg/ml - 2,000 pg/ml
Specificity	Natural and recombinant mouse BMP-2
Immunogen	Expression system for standard: CHO; Immunogen sequence: Q283-R396
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P21274
NCBI Gene ID	12156

Available variants

Conjugation	Size
Not applicable	5 plates/kit