Mouse BMP-10 ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›

Product Description
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. This gene is mapped to 6; 6 D1. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. BMP-10 plays a crucial role in the development of the embryonic heart by acting to stimulate and maintain cardiomyocyte proliferation. It can signal through various receptor complexes usually containing BMPR-1A, BMPR-1B, ALK1, ALK3, or ALK6. The interaction of BMP-10 with its specific receptors can induce signaling initiated by the phosphorylation of SMAD transcription factors, including SMAD1, SMAD5, or SMAD8, but can also induce SMAD independent processes. BMP-10 is structurally related to BMP-9, and both can inhibit endothelial cell proliferation and migration. Recombinant human BMP-10 is a 24.4 kDa homodimeric disulfide-linked protein consisting of two 108 amino acid subunits, which correspond to amino acid residues 317 to 424 of the full-length BMP-10 precursor.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK1809 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Mouse |
| Tested applications | ELISA |
| Gene name | Bmp10 |
| Protein name | Bone morphogenetic protein 10 |
| Sample type | cell culture supernatants, serum and plasma (heparin, EDTA, citrate ). |
| Assay range | 15.6 pg/ml - 1,000 pg/ml |
| Sensitivity | <10 pg/ml |
| Specificity | Natural and recombinant mouse BMP-10 |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: N314-R421 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | Q9R229 |
| NCBI Gene ID | 12154 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Bone morphogenetic protein 10 |
| Also known as | BMP 10; BMP10; BMP-10; bone morphogenetic protein 10 |
| Species reactivity | Mouse |
| Purity | Natural and recombinant mouse BMP-10 |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <10 pg/ml |
| Detection range | 15.6 pg/ml - 1,000 pg/ml |
| Sample types |
cell culture supernatantsserum and plasma (heparinEDTAcitrate ).
See sample validation ›
|
Sample Type Validation
4 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (heparin | |||||
| EDTA | |||||
| citrate ). |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.