Human VAP-1/AOC3 ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›
Product Description
Amine oxidase, copper containing 3, also known as vascular adhesion protein (VAP-1) and HPAO is an enzyme that in humans is encoded by the AOC3 gene on chromosome 17. This protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family and is associated with many vascular diseases. This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK1646 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | AOC3 |
| Protein name | Amine oxidase [copper-containing] 3 |
| Sample type | cell culture supernatants, serum and plasma (heparin, EDTA). |
| Assay range | 0.78 ng/ml - 50 ng/ml |
| Sensitivity | <20 pg/ml |
| Specificity | Natural and recombinant human VAP-1 |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: N2-N763 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | Q16853 |
| NCBI Gene ID | 8639 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Amine oxidase copper-containing 3 |
| Also known as | AOC3; Copper amine oxidase; HPAO; Membrane primary amine oxidase; SSAO; VAP 1; VAP1; Vascular adhesion protein 1 |
| Species reactivity | Human |
| Purity | Natural and recombinant human VAP-1 |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <20 pg/ml |
| Detection range | 0.78 ng/ml - 50 ng/ml |
| Sample types |
cell culture supernatantsserum and plasma (heparinEDTA).
See sample validation ›
|
Sample Type Validation
3 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (heparin | |||||
| EDTA). |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.