Human uPAR / URKR / uPA Receptor ELISA Kit PicoKine®

Human uPAR / URKR / uPA Receptor ELISA Kit PicoKine® (96 Tests). Quantitate Human PLAUR in cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 4pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

The urokinase-type plasminogen activator receptor (uPAR) is a key molecule in the regulation of cell-surface plasminogen activation and, as such, plays an important role in many normal as well as pathological processes. The cDNA for Mo3, an activation antigen expressed by human monocytes and myelomonocytic cell lines after stimulation by a variety of agents. Mo3 expression in vivo is associated predominantly with macrophages in inflammatory sites. It is a highly glycosylated protein of about 50 kD in monocytes where it is anchored to the plasma membrane by glycosyl-phosphatidylinositol linkage. The complete coding sequence of the cDNA has been found to encode 335 amino acids including a predicted signal peptide of 22 residues and a hydrophobic C-terminal portion. Mo3 is identical to the human receptor for the urokinase plasminogen activator. UPAR is a useful prognostic marker for biologically aggressive forms of endometrial cancer. PLAUR is located at chromosome 19q13.1-q13.2. The standard product used in this kit is recombinant human uPAR, consisting of 287 amino acids with the molecular mass of 31KDa.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK0536
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	PLAUR
Protein name	Urokinase plasminogen activator surface receptor
Sample type	cell culture supernatants, serum, plasma (heparin, EDTA) and urine.
Assay range	62.5 pg/ml - 4,000 pg/ml
Sensitivity	<4 pg/ml
Specificity	Natural and recombinant human Upar
Immunogen	Expression system for standard: NS0; Immunogen sequence: L23-R303
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	Q03405
NCBI Gene ID	5329

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.