Human TrkA ELISA Kit PicoKine®

Human TrkA ELISA Kit PicoKine® (96 Tests). Quantitate Human NTRK1 in cell culture supernatants and cell lysates. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Tropomyosin receptor kinase A (TrkA) are efficacious in attenuating skeletal pain.1 TrkA mutants were able to activate signaling cascades and were even more efficient in promoting neurite outgrowth than the wild-type receptor.2 TrkA is part of a sub-family of protein kinases which includes TrkB and TrkC. Also, there are other neurotrophic factors structurally related to NGF: BDNF (for Brain-Derived Neurotrophic Factor), NT-3 (for Neurotrophin-3) and NT-4 (for Neurotrophin-4). While TrkA mediates the effects of NGF, TrkB is bound and activated by BDNF, NT-4, and NT-3. Further, TrkC binds and is activated by NT-3.3 TrkA receptor was found in kehumanoconus-affected corneas, along with an increased level of repressor isoform of Sp3 transcription factor.4

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK0846
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	NTRK1
Protein name	High affinity nerve growth factor receptor
Sample type	cell culture supernatants and cell lysates.
Assay range	156 pg/ml - 10,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human TrkA
Immunogen	Expression system for standard: NS0; Immunogen sequence: A33-E407
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P04629
NCBI Gene ID	4914

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.