Human Trail ELISA Kit EZ-Set™ (DIY Antibody Pairs)
ELISA Antibody Pair supplied by Boster Bio Read more ›
Product Description
In the field of cell biology, TNF-related apoptosis-inducing ligand (TRAIL), is a protein which functions as a ligand which induces the process of cell death called apoptosis. TRAIL has also been designated CD253 (cluster of differentiation 253).Tumor necrosis factor (TNF) family cytokines function as prominent mediators of immune regulation and the inflammatory response. Most TNF family cytokines are expressed as type II transmembrane proteins, with homology confined to approximately 150 C-terminal residues. The TNF ligands interact with a parallel family of receptors. TRAIL binds to the death receptors DR4 (TRAIL-RI) and DR5 (TRAIL-RII). The process of apoptosis is caspase-8-dependent. Caspase-8 activates downstream effector caspases including procaspase-3, -6, and -7, leading to activation of specific kinases. TRAIL also binds the receptors DcR1 and DcR2, which do not contain a cytoplasmic domain (DcR1) or contain a truncated death domain (DcR2). The standard product used in this kit is recombinant human TRAIL with the molecular mass of 21KDa. It is expressed from the amino acids ectoderm T95--G28.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EZ0532 |
| Product category | EZ-Set™ ELISA Kits (Ab Pairs) |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | TNFSF10 |
| Protein name | Tumor necrosis factor ligand superfamily member 10 |
| Sample type | cell culture supernatants, cell lysates, serum, plasma (heparin, EDTA) and saliva. |
| Assay range | 15.6 pg/ml - 1,000 pg/ml |
| Specificity | Natural and recombinant human Trail |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: T95-G281 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | P50591 |
| NCBI Gene ID | 8743 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 5 plates/kit |
Key Facts
| Target | Tumor necrosis factor ligand superfamily member 10 |
| Also known as | Apo 2 ligand; Apo 2L; APO2L; CD253; Protein TRAIL; TL2; TNFSF10; TRAIL |
| Species reactivity | Human |
| Purity | Natural and recombinant human Trail |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Detection range | 15.6 pg/ml - 1,000 pg/ml |
| Sample types |
cell culture supernatantscell lysatesserumplasma (heparinEDTA) and saliva.
See sample validation ›
|
Sample Type Validation
5 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| cell lysates | |||||
| serum | |||||
| plasma (heparin | |||||
| EDTA) and saliva. |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.