Human SPHK1/Sphingosine Kinase 1 ELISA Kit PicoKine®

Human SPHK1/Sphingosine Kinase 1 ELISA Kit PicoKine® (96 Tests). Quantitate Human SPHK1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Sphingosine kinase 1 is an enzyme that in humans is encoded by the SPHK1 gene. The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1- phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1501
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	SPHK1
Protein name	Sphingosine kinase 1
Sample type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Assay range	312 pg/ml - 20,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human SPHK1
Immunogen	Expression system for standard: NS0; Immunogen sequence: M1-L384
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	Q9NYA1
NCBI Gene ID	8877

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.