Human SMAC PicoKine® Quick ELISA Kit

Human SMAC PicoKine® Quick ELISA Kit is a research-use ELISA kit from Boster Bio for measuring Diablo IAP-binding mitochondrial protein in Cell culture supernatant, Cell lysates, serum and plasma (heparin, EDTA). samples from Human. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.

Human Diablo/SMAC PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Human DIABLO in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Diablo homolog, mitochondrial, also known as second mitochondria-derived activator of caspases (SMAC), is a protein that in humans is encoded by the DIABLO gene ( IAP binding protein with low pI). It is mapped to 12q24.31. DIABLO can bind mammalian IAP homolog A (MIHA, or API3) and can also interact with MIHB, MIHC, and OpIAP, the baculoviral IAP. This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Over expression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64.

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