Human Serpin D1 ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›

Product Description
Heparin cofactor II (HCII), a protein encoded by the SERPIND1 gene, is a coagulation factor that inhibits IIa, and is a cofactor for heparin and dermatan sulfate. It is mapped to 22q11.21. This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK1968 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | SERPIND1 |
| Protein name | Heparin cofactor 2 |
| Sample type | cell culture supernatants, serum and plasma (EDTA, citrate) and urine. |
| Assay range | 0.78 ng/ml - 50 ng/ml |
| Sensitivity | <0.1 ng/ml |
| Specificity | Natural and recombinant human Serpin D1 |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: G20-S499 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | P05546 |
| NCBI Gene ID | 3053 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Heparin cofactor 2 |
| Also known as | D22S673; HC II; HC2; HCF2; HCII; Heparin cofactor 2; Heparin cofactor II; HLS2; LS2; Protease inhibitor leuserpin 2; Serpin D1; SERPIND1 |
| Species reactivity | Human |
| Purity | Natural and recombinant human Serpin D1 |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <0.1 ng/ml |
| Detection range | 0.78 ng/ml - 50 ng/ml |
| Sample types |
cell culture supernatantsserum and plasma (EDTAcitrate) and urine.
See sample validation ›
|
Sample Type Validation
3 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (EDTA | |||||
| citrate) and urine. |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.