Human Serpin A1/alpha 1-Antitrypsin ELISA Kit PicoKine®

Human Serpin A1/alpha 1-Antitrypsin ELISA Kit PicoKine® (96 Tests). Quantitate Human SERPINA1 in cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 10pg/ml . The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Alpha-1-antitrypsin?or?α1-antitrypsin? (A1AT,?A1A, or?AAT) is a?protein?belonging to the?serpin?superfamily. It is encoded in humans by the?SERPINA1?gene.?The?gene?is located on the long arm of the fourteenth?chromosome? (14q32.1).The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.Like all?serine protease inhibitors, A1AT has a characteristic?secondary structure?of?beta sheets?and?alpha helices.?Mutations?in these areas can lead to non-functional proteins that can?polymerise?and accumulate in the?liver (infantile hepatic cirrhosis).

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1634
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	SERPINA1
Protein name	Alpha-1-antitrypsin
Sample type	cell culture supernatants, serum, plasma (heparin, EDTA) and urine.
Assay range	1.56 ng/ml - 100 ng/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human Serpin A1
Immunogen	Expression system for standard: NS0; Immunogen sequence: E25-K418
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P01009
NCBI Gene ID	5265

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.