Human RAGE PicoKine® Quick ELISA Kit

Human Rage PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Human AGER in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

RAGE, the Receptor for Advanced Glycation Endproducts, is a 35kD transmembrane receptor of the immunoglobulin super family. It is also known as “AGER”. AGER gene is mapped to chromosome 6p21.3 by mapping by contiguous cosmids and YAC clones and by fluorescence in situ hybridization. The expression of RAGE is particularly increased in neurons close to deposits of amyloid beta peptide and to neurofibrillary tangles. RAGE has been linked to several chronic diseases, which are thought to result from vascular damage. The pathogenesis is hypothesized to include ligand binding upon which RAGE signals activation of the nuclear factor kappa B (NF-kappaB).

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	FEK0827
Product category	Quick ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	AGER
Protein name	Advanced glycosylation end product-specific receptor
Sample type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Assay range	78 pg/ml - 5,000 pg/ml
Sensitivity	<10 pg/ml
Specificity	Natural and recombinant human Rage
Immunogen	Expression system for standard: NS0; Immunogen sequence: Q24-A344
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	B4DNX3
NCBI Gene ID	177

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.