Human PRELP/Prolargin ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›
Product Description
Prolargin?is a?protein?that in humans is encoded by the?PRELP?gene. It is mapped to 1q32.1. The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK2110 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | PRELP |
| Protein name | Prolargin |
| Sample type | cell culture supernatants, serum and plasma (heparin, EDTA, citrate). |
| Assay range | 93.8 pg/ml - 6,000 pg/ml |
| Sensitivity | <50 pg/ml |
| Specificity | Natural and recombinant human PRELP |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: Q21-I382 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | P51888 |
| NCBI Gene ID | 5549 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Prolargin |
| Also known as | Prolargin; Proline-arginine-rich end leucine-rich repeat protein; PRELP; SLRR2A |
| Species reactivity | Human |
| Purity | Natural and recombinant human PRELP |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <50 pg/ml |
| Detection range | 93.8 pg/ml - 6,000 pg/ml |
| Sample types |
cell culture supernatantsserum and plasma (heparinEDTAcitrate).
See sample validation ›
|
Sample Type Validation
4 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (heparin | |||||
| EDTA | |||||
| citrate). |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.