Human PNP ELISA Kit PicoKine®

Human PNP ELISA Kit PicoKine® (96 Tests). Quantitate Human PNP in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 15 pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Purine nucleoside phosphorylase, PNP, PNPase or inosine phosphorylase (EC 2.4.2.1) is an enzyme that in humans is encoded by the NP gene. This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK2258
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	PNP
Protein name	Purine nucleoside phosphorylase
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA)
Assay range	31.2 pg/ml - 2,000 pg/ml
Sensitivity	<15 pg/ml
Specificity	Natural and recombinant human PNP
Immunogen	Expression system for standard: E.coli; Immunogen sequence: M1-S289
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P00491
NCBI Gene ID	4860

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.