Human PILRA ELISA Kit PicoKine®

Human PILRA ELISA Kit PicoKine® (96 Tests). Quantitate Human PILRA in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 75 pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Paired immunoglobin like type 2 receptor alpha is a protein that in humans is encoded by the PILRA gene. Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK2255
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	PILRA
Protein name	Paired immunoglobulin-like type 2 receptor alpha
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA)
Assay range	156 pg/ml - 10,000 pg/ml
Sensitivity	<75 pg/ml
Specificity	Natural and recombinant human PILRA
Immunogen	Expression system for standard: NS0; Immunogen sequence: Q20-T196
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	Q9UKJ1
NCBI Gene ID	29992

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.