Human PEDF/SerpinF1 ELISA Kit PicoKine®

Human PEDF/SerpinF1 ELISA Kit PicoKine® (96 Tests). Quantitate Human SERPINF1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 20pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Pigment epithelium-derived factor (PEDF) is also known as serpin F1 (SERPINF1). In humans, it is encoded by the SERPINF1 gene. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. It suppresses retinal neovascularization and endothelial cell proliferation. And Antiangiogenic function is also conferred by PEDF through inhibition of both VEGFR-1 and VEGFR-2. In addition, the antitumorigenic effects of PEDF are not only due to inhibition of supporting vasculature, but also due to effects on the cancer cells themselves. PEDF is shown to inhibit cancer cell proliferation and increase apoptosis via the FAS/FASL pathway. Expression of PEDF in the human retina is found at 7.4 weeks of gestation, suggesting it may play a role in retinal neuron differentiation.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK0896
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	SERPINF1
Protein name	Pigment epithelium-derived factor
Sample type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Assay range	156 pg/ml - 10,000 pg/ml
Sensitivity	<20 pg/ml
Specificity	Natural and recombinant human PEDF
Immunogen	Expression system for standard: NS0; Immunogen sequence: M1-P418
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P36955
NCBI Gene ID	5176

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.