Human PD-L1/B7-H1 ELISA Kit PicoKine®

Human PD-L1/B7-H1 ELISA Kit PicoKine® (96 Tests). Quantitate Human CD274 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 12pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Programmed death-ligand 1 (PD-L1), also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1), is a protein that in humans is encoded by the CD274 gene. PD-L1 is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. Normally the immune system reacts to foreign antigens where there is some accumulation in the lymph nodes or spleen which triggers a proliferation of antigen-specific CD8+ T cell. The formation of PD-1 receptor / PD-L1 or B7.1 receptor /PD-L1 ligand complex transmits an inhibitory signal which reduces the proliferation of these CD8+ T cells at the lymph nodes and supplementary to that PD-1 is also able to control the accumulation of foreign antigen specific T cells in the lymph nodes through apoptosis which is further mediated by a lower regulation of the gene Bcl-2.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1449
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	CD274
Protein name	Programmed cell death 1 ligand 1
Sample type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Assay range	62.5 pg/ml - 4,000 pg/ml
Sensitivity	<12 pg/ml
Specificity	Natural and recombinant human PD-L1
Immunogen	Expression system for standard: NS0; Immunogen sequence: F19-R238
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	Q9NZQ7
NCBI Gene ID	29126

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.