Human PAM ELISA Kit PicoKine®

Human PAM ELISA Kit PicoKine® (96 Tests). Quantitate Human PAM in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 75pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Peptidyl-glycine alpha-amidating monooxygenase is an enzyme that catalyzes the biosynthesis of many signaling peptides and, in humans, is encoded by the PAM gene. It is mapped to 5q21.1. This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1765
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	PAM
Protein name	Peptidyl-glycine alpha-amidating monooxygenase
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA, citrate).
Assay range	156 pg/ml - 10,000 pg/ml
Sensitivity	<75 pg/ml
Specificity	Natural and recombinant human PAM
Immunogen	Expression system for standard: NS0; Immunogen sequence: M1-V817
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P19021
NCBI Gene ID	5066

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.