ABM-33817
Human NOTCH3 ELISA Kit PicoKine®
ABMIUM Verified™|Collaborator Tested|Boster Bio
ELISA Kit supplied by Boster Bio Read more ›
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Product Description
Human NOTCH3 ELISA Kit PicoKine® (96 Tests). Quantitate Human NOTCH3 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 25 pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.
Neurogenic locus notch homolog protein 3 (Notch 3) is a protein that in humans is encoded by the NOTCH3 gene. This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK2275 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | NOTCH3 |
| Protein name | Neurogenic locus notch homolog protein 3 |
| Sample type | cell culture supernatants, serum and plasma (heparin, EDTA). |
| Assay range | 46.9 pg/ml - 3,000 pg/ml |
| Sensitivity | <25 pg/ml |
| Specificity | Natural and recombinant human NOTCH3 |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: A40-E467 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | Q9UM47 |
| NCBI Gene ID | 4854 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
Product type
ELISA Kit›
Target: Neurogenic locus notch homolog protein 3
| Target | Neurogenic locus notch homolog protein 3 |
| Also known as | CADASIL; CASIL; Notch 3; NOTCH3 |
| Species reactivity | Human |
| Purity | Natural and recombinant human NOTCH3 |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <25 pg/ml |
| Detection range | 46.9 pg/ml - 3,000 pg/ml |
| Sample types |
cell culture supernatantsserum and plasma (heparinEDTA).
See sample validation ›
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Sample Type Validation
3 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum and plasma (heparin | |||||
| EDTA). |
Specifications
Target
Neurogenic locus notch homolog protein 3
Also known as
CADASIL; CASIL; Notch 3; NOTCH3
Purity
Natural and recombinant human NOTCH3
Sensitivity
<25 pg/ml
Detection range
46.9 pg/ml - 3,000 pg/ml
Sample types
cell culture supernatantsserum and plasma (heparinEDTA).
Species reactivity
Human
Storage & Stability
Shipped at
Ambient or cold-chain dependent on product format
Short-term storage
Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Long-term storage
Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Storage conditions
Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Shelf life
Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Compliance & Certifications
RUO
For Research Use Only
Not intended for diagnostic or therapeutic use.
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