ELISA Kit supplied by Boster Bio Read more ›
Human Neutrophil Elastase/ELA2/ELANE ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Neutrophil elastase in Cell culture supernatant, serum and plasma (heparin, EDTA). samples from Human. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.
Human Neutrophil Elastase/ELA2/ELANE ELISA Kit PicoKine® (96 Tests). Quantitate Human ELANE in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 50pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.In humans, neutrophil elastase is encoded by the ELANE gene, which resides on chromosome 19. It is mapped to 19p13.3. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19.
| Collaborator | Boster Bio |
| Partner model | EK2064 |
| Target | Neutrophil elastase |
| Reactivity | Human |
| Applications | ELISA |
| Cross-reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: I30-H267 |
| Sample types | Cell culture supernatant,serum and plasma (heparin,EDTA). |
| Detection range | 0.78 ng/ml - 50 ng/ml |
| Sensitivity | <50 pg/ml |
| Purity | Natural and recombinant human ELANE |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Availability | Available |
Collaborator meets ABMIUM quality standards and overall product performance standards have been met.
For research applications. Not for diagnostic use.
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