Human Neuropilin-1 ELISA Kit PicoKine®

Human Neuropilin-1 ELISA Kit PicoKine® (96 Tests). Quantitate Human NRP1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

NRP1 (Neuropilin 1) also known as NP1, NRP, BDCA4 or VEGF165R, is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor (VEGF) and semaphorin family members. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion. By somatic cell hybrid analysis, the NRP1 gene was mapped to chromosome 10. NRP1 bounds PGF1 with lower affinity. NRP1-mediated interactions are a necessary element in the initiation of the primary immune response and offer another example, like that of agrin, of a molecule shared by neurologic and immunologic synapses. After T-cell contact with DC, T-cell NRP1 colocalized with CD3 in the immunologic synapse and, sometimes, also at the opposite pole of the T cell. Soluble NRP1 interacts in a homophilic fashion with NRP1 on both DC and T cells, and this binding can be inhibited by blocking antibodies to NRP1. Furthermore, selective NRP1 inhibition in this model suppressed neovascular formation substantially.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1353
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	NRP1
Protein name	Neuropilin-1
Sample type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Assay range	0.78 ng/ml - 50 ng/ml
Sensitivity	<20 pg/ml
Specificity	Natural and recombinant human Neuropilin-1
Immunogen	Expression system for standard: NS0; Immunogen sequence: F22-K644
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	O14786
NCBI Gene ID	8829

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.