Human Nephrin ELISA Kit PicoKine®

Human Nephrin ELISA Kit PicoKine® (96 Tests). Quantitate Human NPHS1 in cell culture supernatants, serum and plasma (heparin, EDTA or citrate) . Sensitivity: 50pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Nephrin is a protein necessary for the proper functioning of the renal filtration barrier. It is mapped to 19q13.12. This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK1999
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	NPHS1
Protein name	Nephrin
Sample type	cell culture supernatants, serum and plasma (heparin, EDTA or citrate)
Assay range	156 pg/ml - 10,000 pg/ml
Sensitivity	<50 pg/ml
Specificity	Natural and recombinant human Nephrin
Immunogen	Expression system for standard: NS0; Immunogen sequence: Q23-S1055
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	O60500
NCBI Gene ID	4868

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.