Human Nectin-4/PVRL4 ELISA Kit PicoKine®

Human Nectin-4/PVRL4 ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Nectin-4 in Cell culture supernatant, Serum, plasma(heparin, EDTA), cell lysates and urine. samples from Human. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.

Human Nectin-4/PVRL4 ELISA Kit PicoKine® (96 Tests). Quantitate Human NECTIN4 in cell culture supernatants, serum, plasma(heparin, EDTA), cell lysates and urine. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Nectin-4, also known as PVRL4, is an adhesion receptor of the immunoglobulin superfamily and functions in cell-cell adhesion. This gene is mapped to chromosome 1q23.3. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

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