Human Kallikrein-6 / KLK6 ELISA Kit PicoKine®

Human Kallikrein-6 / KLK6 ELISA Kit PicoKine® (96 Tests). Quantitate Human KLK6 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 3pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

KLK6 (Kallikrein-related peptidase 6), also called KALLIKREIN 6, NEUROSIN, PROTEASE M, ZYME or PRSS9, is a protein that in humans is encoded by the KLK6 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary, prostate, and ovarian cancers, but was not detected in any metastases of these cancers. The KLK6 gene is mapped on 19q13.41. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Upon cellular stress, neurosin was released from mitochondria to the cytosol, which resulted in the increase of degraded alpha-synuclein species. Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EK0818
Product category	PicoKine® ELISA Kits
Reactive species	Human
Tested applications	ELISA
Gene name	KLK6
Protein name	Kallikrein-6
Sample type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Assay range	78 pg/ml - 5,000 pg/ml
Sensitivity	<3 pg/ml
Specificity	Natural and recombinant human Kallikrein-6
Immunogen	Expression system for standard: NS0; Immunogen sequence: L22-K244
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	Q92876
NCBI Gene ID	5653

Available variants

Conjugation	Size
Not applicable	96 wells/kit, with removable strips.