Human IL-33 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Human IL-33 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human IL33 in cell culture supernatants, serum, plasma (heparin, EDTA) and cell lysates.

Interleukin 33 (IL-33) is a cytokine belonging to the IL-1 superfamily. The IL33 gene maps to chromosome 9p24.1 by using of genomic database analysis. Recombinant mature human IL33 bound to ST2. The induction of type 2 cytokines by IL-33 in vivo is believed to induce the severe pathological changes observed in mucosal organs following administration of IL-33. IL33, an alarmin released from necrotic cells, is necessary for potent CD8 + T cell (CTL) responses to replicating, prototypic RNA, and DNA viruses in mice. IL33 prevented the downregulation of CXCR2 and inhibition of chemotaxis induced by activation of TLR4, and found that IL33 reverses the TLR4-induced reduction of CXCR2 expression via the inhibition of expression of GRK2.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EZ0929
Product category	EZ-Set™ ELISA Kits (Ab Pairs)
Reactive species	Human
Tested applications	ELISA
Gene name	IL33
Protein name	Interleukin-33
Sample type	cell culture supernatants, serum, plasma (heparin, EDTA) and cell lysates.
Assay range	15.6 pg/ml - 1,000 pg/ml
Specificity	Natural and recombinant human IL-33
Immunogen	Expression system for standard: E.coli; Immunogen sequence: S112-T270
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	O95760
NCBI Gene ID	90865

Available variants

Conjugation	Size
Not applicable	5 plates/kit