Human IL-18BP ELISA Kit PicoKine®
ELISA Kit supplied by Boster Bio Read more ›

Product Description
Interleukin-18-binding protein, also known as IL18BPa, is a protein that in humans is encoded by the IL18BP gene. It is mapped to 11q13.4. The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. It has been found that IL18BP expression in intestinal tissue is increased in endothelial cells as well as cells of the submucosa and overlying lymphoid aggregates in Crohn disease.
Product information
| Supplier | Boster Bio |
|---|---|
| ABMIUM evidence status | ABMIUM Verified™ collaborator-tested data |
| Catalogue reference | EK1282 |
| Product category | PicoKine® ELISA Kits |
| Reactive species | Human |
| Tested applications | ELISA |
| Gene name | IL18BP |
| Protein name | Interleukin-18-binding protein |
| Sample type | cell culture supernatants, serum, plasma (heparin, EDTA) and urine. |
| Assay range | 93.7 pg/ml - 6,000 pg/ml |
| Sensitivity | <10 pg/ml |
| Specificity | Natural and recombinant human IL-18BP |
| Immunogen | Expression system for standard: NS0; Immunogen sequence: T31-G194 |
| Storage | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| UniProt | O95998 |
| NCBI Gene ID | 10068 |
Available variants
| Conjugation | Size |
|---|---|
| Not applicable | 96 wells/kit, with removable strips. |
Key Facts
| Target | Interleukin-18-binding protein |
| Also known as | IL 18BP; IL18BP; IL-18BP; IL18BPa; interleukin 18 binding protein; Tadekinig alfa |
| Species reactivity | Human |
| Purity | Natural and recombinant human IL-18BP |
| Shelf life | Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
| Sensitivity | <10 pg/ml |
| Detection range | 93.7 pg/ml - 6,000 pg/ml |
| Sample types |
cell culture supernatantsserumplasma (heparinEDTA) and urine.
See sample validation ›
|
Sample Type Validation
4 sample types| Sample Type | SERUM | PLASMA (EDTA) | URINE | CSF | CELL SUPERNATANT |
|---|---|---|---|---|---|
| cell culture supernatants | |||||
| serum | |||||
| plasma (heparin | |||||
| EDTA) and urine. |
Specifications
Storage & Stability
Compliance & Certifications
Not intended for diagnostic or therapeutic use.