Human IL-10 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Human IL-10 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human IL10 in cell culture supernatants, serum and plasma ( heparin, EDTA, citrate).

Interleukin-10, also called cytokine synthesis inhibitory factor, is implicated in tumorigenesis, and it has been shown that polymorphisms in its gene promoter correlate with differential amounts of production. IL-10 is an important cytokine with anti-inflammatory, anti-immune, and antifibrotic functions. It is also an important regulatory cytokine whose involvement extends into diverse areas of the human immune system. IL-10 is a recently described natural endogenous immunosuppressive cytokine that has been identified in human, murine, and other organisms. IL-10 significantly affects chemokine biology, because human IL-10 inhibits chemokine production and is a specific chemotactic factor for CD8+ T cells. It suppresses the ability of CD4+ T cells, but not CD8+ T cells, to migrate in response to IL-8. Interleukin-10 gene polymorphisms and interleukin-10 production capability may contribute to the development of skin squamous cell carcinomas after renal transplantation.1 The interleukin-10 locus contributes to the heritability of psoriasis susceptibility. With regard to sudden infant death, IL-10 is of special interest. This is an immunoregulatory cytokine that plays an important role in the development of infectious disease The mIL-10 gene is mapped to mouse chromosome 1 and the hIL-10 gene is also mapped to human chromosome 1. The standard product used in this kit is recombinant human IL-10, consisting of 160 amino acids with the molecular mass of 18.6KDa.

Product information

Supplier	Boster Bio
ABMIUM evidence status	ABMIUM Verified™ collaborator-tested data
Catalogue reference	EZ0416
Product category	EZ-Set™ ELISA Kits (Ab Pairs)
Reactive species	Human
Tested applications	ELISA
Gene name	IL10
Protein name	Interleukin-10
Sample type	cell culture supernatants, serum and plasma ( heparin, EDTA, citrate).
Assay range	7.8 pg/ml - 500 pg/ml (cell culture supernates) 3.4 pg/ml - 250 pg/ml (human serum, plasma)
Specificity	Natural and recombinant human IL-10
Immunogen	Expression system for standard: E.coli; Immunogen sequence: S19-N178
Storage	Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
UniProt	P22301
NCBI Gene ID	3586

Available variants

Conjugation	Size
Not applicable	5 plates/kit